Yo Gabba Gabba! is hosted by a character named DJ Lance Rock, and five toy monsters: Brobee, Foofa, Muno, Plex, and Toodee. It features The MC Bat Commander and Ricky Fitness, two members of The Aquabats, and Adam Deibert (formerly of the Aquabats) as the voice of Muno the Cyclops.

The show features a wide variety of guests: The Shins, The Aggrolites, Cornelius, Biz Markie, Shiny Toy Guns, Supernova, Mark Mothersbaugh, Rahzel, The Postmarks, Sugarland, Tony Hawk, Low, Laila Ali, Elijah Wood, The Aquabats, and Mýa have all been confirmed to appear in the first season.

The absurd style of humor used in the show is intended, like The Aquabats, to appeal to adults through its manic, frenzied approach to wholesome messages, while at the same time carrying all the family-friendly content of the average Nick Jr. program.

Among the varied animation sequences during the show is Super Martian Robot Girl, designed by indie cartoonists Evan Dorkin and Sarah Dyer.

Retailer and toy manufacturer, Kidrobot makes and sells figures of each of the five characters.

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	RARE~BROBEE~YO GABBA GABBA~TODDLER~T-SHIRT~SIZE 2T, 2 Price: $29.99 (0 Bids) Sale Ends: 7h 41m
	Yo Gabba Gabba Pals plush MUNO stuffed figure NickJr Price: $9.95 (0 Bids) Buy It Now Price: $19.95 Sale Ends: 8h 26m
	Yo Gabba Gabba Pals plush PLEX stuffed figure NickJr Price: $9.95 (1 Bids) Sale Ends: 8h 27m
	YO GABBA GABBA (Kidrobot) - MINT IN BOX - FOOFA Buy It Now Price: $29.95 Sale Ends: 8h 49m
	YO GABBA GABBA TOY (Kidrobot) - MINT IN BOX - MUNO Buy It Now Price: $29.95 Sale Ends: 8h 49m
	Awesome Yo Gabba Gabba Stereo Tank Top Size Large NWT Buy It Now Price: $40.00 Sale Ends: 17h 38m
	Yo Gabba Gabba Plush Foofa No Reserve!! FREE SHIPPING! Price: $40.00 (1 Bids) Sale Ends: 20h 10m
	NIB New Yo Gabba Gabba Plex Car Buggy RARE Nick Jr Price: $34.99 (0 Bids) Buy It Now Price: $44.99 Sale Ends: 22h 1m
	New Yo Gabba Gabba Tote Bag Purse RARE HTF Brobee Plex Price: $29.99 (0 Bids) Buy It Now Price: $49.99 Sale Ends: 22h 33m
	LOT 3 Kidrobot Yo Gabba Gabba Figures Muno Plex Toodee Price: $21.01 (3 Bids) Sale Ends: 1d 2h 32m
	NWT YO GABBA GABBA plush pals MUNO Nick Jr. Price: $5.00 (4 Bids) Sale Ends: 1d 6h 29m
	NWT YO GABBA GABBA plush pals BROBEE Nick Jr. Price: $10.50 (7 Bids) Sale Ends: 1d 6h 31m
	Yo Gabba Gabba PLEX Figure BUGGY Car Truck Set! Buy It Now Price: $26.88 Sale Ends: 1d 17h 15m
	NWT Yo Gabba Gabba Brobee Party Tummy T-Shirt Sz 3T Buy It Now Price: $24.99 Sale Ends: 2d 40m
	NWT Yo Gabba Gabba Muno Rocks Guitar T-Shirt Sz 3T Buy It Now Price: $24.99 Sale Ends: 2d 56m
	Yo Gabba Gabba DRIVIN FRIENDS Train Car BROBEE Vehicle Buy It Now Price: $17.88 Sale Ends: 2d 6h 51m
	Yo Gabba Gabba DRIVIN FRIENDS Train Car MUNO Vehicle Buy It Now Price: $17.88 Sale Ends: 2d 6h 52m
	YO GABBA GABBA = NICK JR = PROMOTIONAL DVD = NEW Price: $1.97 (0 Bids) Sale Ends: 2d 22h 10m
	KidRobot Yo Gabba Gabba Kidrobot Muno New Price: $39.86 (0 Bids) Sale Ends: 2d 23h 39m
	Yo Gabba Gabba MUNO Silly Heads SILLIES OUT Song! Buy It Now Price: $24.88 Sale Ends: 3d 3h 53m